• 腾博tengbo9885

    Ponatinib Hydrochloride

    ICLUSIG®

    About ICLUSIG®

    1. Marketed by Takeda Pharmaceutical Company Limited
    2. Orally bioavailable Bcr-Abl tyrosine kinase inhibitor
    3. Treatment of adult patients with treatment-resistant or intolerant chronic phase (CP) chronic myeloid leukemia (CML), accelerated phase (AP) or blast phase (BP) CML or Philadelphia chromosome–positive (Ph+) CML for which no other kinase inhibitors are indicated, and T315I-positive CML or T315I-positive Ph+ ALL

    Approvals

    1. First U.S. approval: December 14, 2012
    2. First E.U. approval: July 1, 2013

    Constraint date forecast:

    1. Patent expiry: 2026 (United States)
    2. Patent expiry: 2027 (Japan)
    3. SPC expiry: 2028 (European Union)

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